Organocatalytic γ′[C(sp3)–H] Functionalization of Ynones: An Unusual Approach for the Cyclopentannulation of Benzothiophenes
| dc.contributor.author | Grover, J. | |
| dc.contributor.author | Raghu, M. | |
| dc.contributor.author | Hazra, R. | |
| dc.contributor.author | Mondal, A. | |
| dc.contributor.author | Ramasastry, S.S.V. | |
| dc.date.accessioned | 2020-11-23T10:44:01Z | |
| dc.date.available | 2020-11-23T10:44:01Z | |
| dc.date.issued | 2018 | |
| dc.description.abstract | An efficient organocatalytic approach for the cyclopenta[b]annulation of benzothiophenes via γ′[C(sp3)–H] functionalization of ynones is described. Nucleophilic addition of an organophosphine to the designed ynones generates heteroaryl-based ortho-quinodimethanes (oQDMs), which undergo carbocyclization to provide a variety of cyclopenta-fused benzothiophenes. This approach also constitutes an unusual organophosphine-catalyzed intramolecular hydroalkylation of ynones. | en_US |
| dc.identifier.citation | Synthesis (Germany), 50(7), pp. 1462-1470 | en_US |
| dc.identifier.other | 10.1055/s-0036-1591526 | |
| dc.identifier.uri | https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0036-1591526 | |
| dc.identifier.uri | http://hdl.handle.net/123456789/2059 | |
| dc.language.iso | en | en_US |
| dc.publisher | Georg Thieme Verlag | en_US |
| dc.subject | Organophosphines | en_US |
| dc.subject | Hydroalkylation | en_US |
| dc.subject | Cyclopentannulation | en_US |
| dc.subject | Ynones | en_US |
| dc.subject | Benzothiophenes | en_US |
| dc.title | Organocatalytic γ′[C(sp3)–H] Functionalization of Ynones: An Unusual Approach for the Cyclopentannulation of Benzothiophenes | en_US |
| dc.type | Article | en_US |