One-Pot Relay Gold(I) and Brønsted Acid Catalysis: Cyclopenta[b]annulation of Indoles via Hydroamination/Nazarov-Type Cyclization Cascade of Enynols
| dc.contributor.author | Dhiman, Seema | |
| dc.contributor.author | Ramasastry, S.S.V. | |
| dc.date.accessioned | 2020-12-07T08:40:22Z | |
| dc.date.available | 2020-12-07T08:40:22Z | |
| dc.date.issued | 2015 | |
| dc.description.abstract | An expedient relay gold(I) and Brønsted acid catalyzed hydroamination/Nazarov cyclization of 1-(2-aminophenyl)pent-4-en-2-ynols for the synthesis of various polyfunctionalized cyclopenta[b]indoles is described. The synthetic utility of this method has been demonstrated by the synthesis of a few unprecedented pentacyclic indoles and indole–steroidal hybrids. Further, the new methodology has been successfully applied to the enantioselective synthesis of core carbon structure of the polyveoline family of natural products. | en_US |
| dc.identifier.citation | Organic Letters, 17 (20) | en_US |
| dc.identifier.other | 10.1021/acs.orglett.5b02632 | |
| dc.identifier.uri | https://pubs.acs.org/doi/10.1021/acs.orglett.5b02632 | |
| dc.identifier.uri | http://hdl.handle.net/123456789/2746 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | American Chemical Society | en_US |
| dc.subject | Cyclization | en_US |
| dc.subject | Pharmaceuticals | en_US |
| dc.subject | Quinolines | en_US |
| dc.subject | Indoles | en_US |
| dc.title | One-Pot Relay Gold(I) and Brønsted Acid Catalysis: Cyclopenta[b]annulation of Indoles via Hydroamination/Nazarov-Type Cyclization Cascade of Enynols | en_US |
| dc.type | Article | en_US |