(2 S)-2-[(Phenylsulfinyl)methyl]pyrrolidine-catalyzed efficient stereoselective michael addition of cyclohexanone and cyclopentanone to nitroolefins
| dc.contributor.author | Khullar, S. | |
| dc.contributor.author | Mandal, S.K. | |
| dc.date.accessioned | 2020-12-10T06:16:27Z | |
| dc.date.available | 2020-12-10T06:16:27Z | |
| dc.date.issued | 2013 | |
| dc.description | Only IISERM authors are available in the record. | |
| dc.description.abstract | (2S)-2-[(Phenylsulfinyl)methyl]pyrrolidine, derived from l-proline, has been demonstrated as an efficient organocatalyst for the asymmetric Michael addition of cyclohexanone and cyclopentanone to β-nitrostyrenes. This pyrrolidine-based catalyst bearing a sulfoxide moiety was used to synthesize various γ-nitro carbonyl compounds in high yield (up to 97%) with excellent stereoselectivity (up to >99:1 dr and >99% ee) without the use of any additive. | en_US |
| dc.identifier.citation | Synthesis (Germany), 45(10), pp.1406-1413. | en_US |
| dc.identifier.other | 10.1055/s-0032-1316917 paper | |
| dc.identifier.uri | https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0032-1316917 | |
| dc.identifier.uri | http://hdl.handle.net/123456789/2931 | |
| dc.language.iso | en | en_US |
| dc.publisher | Thieme | en_US |
| dc.subject | Michael addition reaction | en_US |
| dc.subject | Organocatalyst | en_US |
| dc.subject | Amino sulfoxide | en_US |
| dc.subject | Nitroolefins | en_US |
| dc.title | (2 S)-2-[(Phenylsulfinyl)methyl]pyrrolidine-catalyzed efficient stereoselective michael addition of cyclohexanone and cyclopentanone to nitroolefins | en_US |
| dc.type | Article | en_US |