Magnetically separable nano Fe3O4 as highly efficient and reusable heterogeneous catalyst for the regio-and stereoselective synthesis of β-amino alcohols

Abstract

Magnetically recoverable and nano Fe3O4-catalyzed ring opening of aliphatic, alicyclic and aromatic epoxides with a variety of amines under solvent free condition is reported . Nano Fe3Os- catalyzed epoxide opening gave various β-amino alcohols in good to excellent yields with very high regio-and stereoselectivity. The catalyst can be recovered and reused up to ten cycles.