Pd(II)-Catalyzed Direct β-Arylation of C(sp3)-H Bonds of Aliphatic and Alicyclic Carboxamides Via One-pot Method
| dc.contributor.author | Mohan, Sruthi | |
| dc.date.accessioned | 2016-09-03T05:45:48Z | |
| dc.date.available | 2016-09-03T05:45:48Z | |
| dc.date.issued | 2016-09-03 | |
| dc.description.abstract | A step economical one-pot multicomponent reaction protocol comprising the installation of the bidentate directing group followed by the Pd(II)-catalyzed C-H activation and β-arylation of C(sp3)-H bonds of carboxamides is reported. Accordingly, the reaction of a mixture of an acid chloride, bidentate ligand (e.g., 8-aminoquinoline), and an aryl iodide in the presence of the Pd(OAc)2 catalyst and Ag2CO3 additive directly afforded the corresponding β-C-H -arylated N-(quinolin-8-yl) carboxamide derivatives. | en_US |
| dc.description.sponsorship | IISER-M | en_US |
| dc.guide | Babu, S.A. | |
| dc.identifier.uri | http://hdl.handle.net/123456789/603 | |
| dc.language.iso | en | en_US |
| dc.publisher | IISER-M | en_US |
| dc.subject | Chemistry | en_US |
| dc.subject | Alicyclic Carboxamides | en_US |
| dc.subject | Aliphatic Carboxamides | en_US |
| dc.title | Pd(II)-Catalyzed Direct β-Arylation of C(sp3)-H Bonds of Aliphatic and Alicyclic Carboxamides Via One-pot Method | en_US |
| dc.type | Thesis | en_US |