C(sp3)–H Activation Enabled by (η3-Indolylmethyl)palladium Complexes: Synthesis of Monosubstituted Tetrahydrocarbazoles
| dc.contributor.author | Kumar, Ketan | |
| dc.contributor.author | Vivekanand, T. | |
| dc.contributor.author | Singh, Bara | |
| dc.contributor.author | Ramasastry, S. S. V. | |
| dc.date.accessioned | 2023-08-21T11:19:41Z | |
| dc.date.available | 2023-08-21T11:19:41Z | |
| dc.date.issued | 2021 | |
| dc.description | Only IISERM authors are available in the record. | en_US |
| dc.description.abstract | The synthesis of monosubstituted tetrahydrocarbazoles is achieved via the palladium-catalyzed formal [4+2] cycloaddition of 2-alkyl-3-indolylmethyl carbonates and monosubstituted olefins. The transformation demonstrates an unusual C(sp3)–H activation enabled by (η3-indolylmethyl)palladium complexes. The regioselectivity is found to be dependent on the nature of the substituent across the olefin component. Elaborate mechanistic studies are performed, and the synthetic utility of the products is also demonstrated. | en_US |
| dc.identifier.citation | Synthesis, 54(04), 943–952. | en_US |
| dc.identifier.uri | https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-1516-7960 | |
| dc.identifier.uri | http://hdl.handle.net/123456789/4958 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Thieme | en_US |
| dc.subject | C–H functionalization | en_US |
| dc.subject | tetrahydrocarbazoles | en_US |
| dc.title | C(sp3)–H Activation Enabled by (η3-Indolylmethyl)palladium Complexes: Synthesis of Monosubstituted Tetrahydrocarbazoles | en_US |
| dc.type | Article | en_US |