Construction of Functionalized Carbocycles Having Contiguous Tertiary Carbinol and All‐Carbon Stereogenic Centers

Abstract

The indium‐mediated installation of a stereoarray that consists of contiguous tertiary carbinol and all‐carbon stereocenters in functionalized carbocyclic building blocks and bicyclic lactones is presented. The absolute stereochemistry of the products was established for the highly diastereofacial selective addition of allyl and propargyl indiums to α‐alkyl‐α‐(ethoxycarbonyl)cycloalkanones.