A Highly Efficient Base-Metal Catalyst: Chemoselective Reduction of Imines to Amines Using An Abnormal-NHC–Fe(0) Complex
| dc.contributor.author | Adhikari, D. | |
| dc.date.accessioned | 2020-12-02T06:33:23Z | |
| dc.date.available | 2020-12-02T06:33:23Z | |
| dc.date.issued | 2016 | |
| dc.description | Only IISERM authors are available in the record. | |
| dc.description.abstract | A base-metal, Fe(0)-catalyzed hydrosilylation of imines to obtain amines is reported here which outperforms its noble-metal congeners with the highest TON of 17000. The catalyst, (aNHC)Fe(CO)4, works under very mild conditions, with extremely low catalyst loading (down to 0.005 mol %), and exhibits excellent chemoselectivity. The facile nature of the imine reduction under mild conditions has been further demonstrated by reducing imines towards expensive commercial amines and biologically important N-alkylated sugars, which are difficult to achieve otherwise. A mechanistic pathway and the source of chemoselectivity for imine hydrosilylation have been proposed on the basis of the well-defined catalyst and isolable intermediates along the catalytic cycle. | en_US |
| dc.identifier.citation | Organometallics, 35(17), pp.2930–2937. | en_US |
| dc.identifier.other | https://doi.org/10.1021/acs.organomet.6b00478 | |
| dc.identifier.uri | https://pubs.acs.org/doi/abs/10.1021/acs.organomet.6b00478 | |
| dc.identifier.uri | http://hdl.handle.net/123456789/2481 | |
| dc.language.iso | en | en_US |
| dc.publisher | American Chemical Society | en_US |
| dc.subject | Catalyzed | en_US |
| dc.subject | Hydrosilylation | en_US |
| dc.subject | Exhibits | en_US |
| dc.subject | Chemoselectivity | en_US |
| dc.title | A Highly Efficient Base-Metal Catalyst: Chemoselective Reduction of Imines to Amines Using An Abnormal-NHC–Fe(0) Complex | en_US |
| dc.type | Article | en_US |