NHC catalysed trimethylsilylation of terminal alkynes and indoles with Ruppert's reagent under solvent free conditions
| dc.contributor.author | Arde, Panjab | |
| dc.contributor.author | Reddy, V. | |
| dc.contributor.author | Anand, R.V. | |
| dc.date.accessioned | 2020-12-14T07:06:43Z | |
| dc.date.available | 2020-12-14T07:06:43Z | |
| dc.date.issued | 2014 | |
| dc.description.abstract | n organo-catalytic protocol for the trimethylsilylation of terminal alkynes employing Ruppert's reagent (CF3SiMe3) as a trimethylsilyl source has been developed under solvent and fluoride free conditions. This method was found to be very effective as a variety of terminal alkynes bearing aliphatic or aromatic substituents underwent smooth transformation to their corresponding silylated products in excellent yields within a few minutes using N-heterocyclic carbene as an organo-catalyst. This methodology was also applied to the chemospecific N-silylation of indoles. | en_US |
| dc.identifier.citation | RSC Advances, 4(91), pp.49775-49779. | en_US |
| dc.identifier.other | https://doi.org/10.1039/C4RA08727E | |
| dc.identifier.uri | https://pubs.rsc.org/en/content/articlelanding/2014/RA/C4RA08727E#!divAbstract | |
| dc.identifier.uri | http://hdl.handle.net/123456789/3105 | |
| dc.language.iso | en | en_US |
| dc.publisher | Royal Society of Chemistry | en_US |
| dc.subject | Terminal alkynes | en_US |
| dc.subject | Trimethyl silylation | en_US |
| dc.subject | NHC catalysed | en_US |
| dc.title | NHC catalysed trimethylsilylation of terminal alkynes and indoles with Ruppert's reagent under solvent free conditions | en_US |
| dc.type | Article | en_US |