Nickel-Catalyzed Selective Synthesis of α-Alkylated Ketones via Dehydrogenative Cross-Coupling of Primary and Secondary Alcohols
| dc.contributor.author | Bains, Amreen K | |
| dc.contributor.author | Biswas, Ayanangshu | |
| dc.contributor.author | Adhikari, Debashis | |
| dc.date.accessioned | 2023-08-17T12:17:17Z | |
| dc.date.available | 2023-08-17T12:17:17Z | |
| dc.date.issued | 2021 | |
| dc.description | Only IISERM authors are available in the record | en_US |
| dc.description.abstract | Herein,we describean isolable,air-stable,homogeneous,nickel catalystthat performsdehydrogenativecross-couplingreactionbetweensecondaryand primaryalcoholsto result α-alkylatedketoneproductsselectively. The sequenceof stepsinvolvein this one-potreactionis dehydrogenationof both alcohols,condensationbetweenthe ketoneand the aldehyde,and hydrogenationof the in situ-generatedα,β-unsaturatedketone.Preliminarymechanisticinvestigationhints a radicalmechanismfollowingborrowinghydrogenreaction | en_US |
| dc.identifier.citation | Advanced Synthesis & Catalysis, 364(1), 47–52. | en_US |
| dc.identifier.uri | https://onlinelibrary.wiley.com/doi/10.1002/adsc.202101077 | |
| dc.identifier.uri | http://hdl.handle.net/123456789/4790 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Wiley | en_US |
| dc.subject | nickel catalysis | en_US |
| dc.subject | cross-coupling | en_US |
| dc.subject | secon-dary alcohols | en_US |
| dc.subject | radicalreaction | en_US |
| dc.title | Nickel-Catalyzed Selective Synthesis of α-Alkylated Ketones via Dehydrogenative Cross-Coupling of Primary and Secondary Alcohols | en_US |
| dc.type | Article | en_US |