Zinc-Mediated Allylation Followed by Lactonization of Dialkyl 2-(3-Oxo-1,3-diarylpropyl)malonates: Construction of δ-Lactones with Multiple Stereocenters
| dc.contributor.author | Reddy, C. | |
| dc.contributor.author | Babu, S.A. | |
| dc.date.accessioned | 2020-12-08T05:12:31Z | |
| dc.date.available | 2020-12-08T05:12:31Z | |
| dc.date.issued | 2015 | |
| dc.description.abstract | A variety of polysubstituted δ-lactones containing three or four stereocenters were prepared from various dialkyl 2-(3-oxo-1,3-diarylpropyl)malonates by a Barbier-type zinc-mediated allylation or cyclohexenylation of the keto group, followed by intramolecular lactonization/transesterification. The stereochemistry of the major isomers was confirmed by X-ray crystal structure analysis of representative compounds | en_US |
| dc.identifier.citation | Synlett, 26(15) | en_US |
| dc.identifier.other | 10.1055/s-0035-1560052 | |
| dc.identifier.uri | https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0035-1560052 | |
| dc.identifier.uri | http://hdl.handle.net/123456789/2781 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Georg Thieme Verlag | en_US |
| dc.subject | allylation | en_US |
| dc.subject | diastereoselectivity | en_US |
| dc.subject | lactones | en_US |
| dc.subject | stereoselective synthesis | en_US |
| dc.title | Zinc-Mediated Allylation Followed by Lactonization of Dialkyl 2-(3-Oxo-1,3-diarylpropyl)malonates: Construction of δ-Lactones with Multiple Stereocenters | en_US |
| dc.type | Article | en_US |