Phosphine-Catalyzed Intramolecular Vinylogous Aldol Reaction of α-Substituted Enones
| dc.contributor.author | Mondal, Atanu | |
| dc.contributor.author | Satpathi, Bishnupada | |
| dc.contributor.author | Ramasastry, S. S. V. | |
| dc.date.accessioned | 2023-08-19T13:01:48Z | |
| dc.date.available | 2023-08-19T13:01:48Z | |
| dc.date.issued | 2022 | |
| dc.description | Only IISER Mohali authors are available in the record. | en_US |
| dc.description.abstract | We demonstrate the first phosphine-catalyzed intramolecular vinylogous aldol reaction (IVAR) of α-substituted enones. This strategy provides access to various pentannulated (hetero)arenes and dibenzocycloheptanones incorporated with two contiguous stereocenters, one of which is an all-carbon quaternary center. The scope of this work is further broadened through elaborations of the IVAR adducts to (i) benzannulated nine-membered carbocyclic systems, (ii) interesting classes of 1,3-dienes, 1,3,5-trienes, and 1-yn-3,5-dienes, and (iii) the analogs of echinolactone D and russujaponol F. | en_US |
| dc.identifier.citation | Organic Letters, 24(1), 256-261. | en_US |
| dc.identifier.uri | https://doi.org/10.1021/acs.orglett.1c03913 | |
| dc.identifier.uri | http://hdl.handle.net/123456789/4907 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | ACS Publications | en_US |
| dc.subject | Phosphine-Catalyzed | en_US |
| dc.subject | Intramolecular Vinylogous | en_US |
| dc.subject | Aldol Reaction of α-Substituted Enones | en_US |
| dc.title | Phosphine-Catalyzed Intramolecular Vinylogous Aldol Reaction of α-Substituted Enones | en_US |
| dc.type | Article | en_US |