Synthesis of 1-Naphthol-based Unsymmetrical Triarylmethanes: Heck-type Desulfitative Reaction of Arylsulfonyl Chlorides with Tetralone-derived Chalcones

Abstract

We report the preliminary results of an investigation comprising of the synthesis of 1-naphthol-based unsymmetrical triarylmethanes via the Pd-catalyzed Heck-type desulfitative reaction and conjugate addition of arylsulfonyl chlorides with tetralone-derived chalcones. Unsymmetrical triarylmethanes are valuable molecules in organic-, medicinal and materials chemistry. This work is a contribution towards enriching the library of unsymmetrical triarylmethanes.