Structure based drug discovery for designing leads for the non-toxic metabolic targets in multi drug resistant Mycobacterium tuberculosis
| dc.contributor.author | Jainanarayan, A.K. | |
| dc.date.accessioned | 2020-11-17T09:04:31Z | |
| dc.date.available | 2020-11-17T09:04:31Z | |
| dc.date.issued | 2017 | |
| dc.description | Only IISERM authors are available in the record. | |
| dc.description.abstract | The problem of drug resistance and bacterial persistence in tuberculosis is a cause of global alarm. Although, the UN's Sustainable Development Goals for 2030 has targeted a Tb free world, the treatment gap exists and only a few new drug candidates are in the pipeline. In spite of large information from medicinal chemistry to 'omics' data, there has been a little effort from pharmaceutical companies to generate pipelines for the development of novel drug candidates against the multi drug resistant Mycobacterium tuberculosis. | en_US |
| dc.identifier.citation | Journal of Translational Medicine, 15 (1) | en_US |
| dc.identifier.other | 10.1186/s12967-017-1363-9 | |
| dc.identifier.uri | https://pubmed.ncbi.nlm.nih.gov/29268770/ | |
| dc.identifier.uri | http://hdl.handle.net/123456789/1678 | |
| dc.language.iso | en | en_US |
| dc.publisher | Pubmed. | en_US |
| dc.subject | Drug development | en_US |
| dc.subject | Drug resistance | en_US |
| dc.subject | Mycobacterium tuberculosis | en_US |
| dc.subject | Non-toxic targets | en_US |
| dc.subject | Structural biology | en_US |
| dc.subject | Systems biology | en_US |
| dc.title | Structure based drug discovery for designing leads for the non-toxic metabolic targets in multi drug resistant Mycobacterium tuberculosis | en_US |
| dc.type | Article | en_US |