Palladium-Catalyzed Double Activation and Arylation of 2° and 3° C(sp3)–H Bonds of the Norbornane System: Formation of a C–C Bond at the Bridgehead Carbon and Bridgehead Quaternary Stereocenter

dc.contributor.authorParella, R.
dc.contributor.authorBabu, S.A.
dc.date.accessioned2020-12-11T10:38:51Z
dc.date.available2020-12-11T10:38:51Z
dc.date.issued2014
dc.description.abstractPd-catalyzed activation and direct arylation of both 2° and the bridgehead 3° (sp3) C-H bonds and an unprecedented C-C bond formation at the bridgehead carbon of the norbornane system are reported. The assembly of bridgehead-substituted norbornane frameworks having contiguous stereocenters was accomplished. X-ray crystal structure analysis of representative molecules unambiguously established the stereochemistry.en_US
dc.identifier.citationSynlett, 25(10), pp.1395-1402.en_US
dc.identifier.other10.1055/s-0033-1341242
dc.identifier.urihttps://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0033-1341242
dc.identifier.urihttp://hdl.handle.net/123456789/3060
dc.language.isoenen_US
dc.publisherGeorg Thieme Verlagen_US
dc.subjectArylationen_US
dc.subjectBridgehead substitutionen_US
dc.subjectC–H activationen_US
dc.subjectDiastereoselectivityen_US
dc.subjectPalladiumen_US
dc.subjectStereoselective synthesisen_US
dc.titlePalladium-Catalyzed Double Activation and Arylation of 2° and 3° C(sp3)–H Bonds of the Norbornane System: Formation of a C–C Bond at the Bridgehead Carbon and Bridgehead Quaternary Stereocenteren_US
dc.typeArticleen_US

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