Pd(II)‐catalyzed, Picolinamide‐aided sp2 γ−C−H Functionalization of Phenylglycinol: Access to γ−C−H Arylated, Alkylated and Halogenated Phenylglycinol Scaffolds
| dc.contributor.author | Singh, Prabhakar | |
| dc.contributor.author | Arulananda Babu, S. | |
| dc.contributor.author | Aggarwal, Y. | |
| dc.contributor.author | Patel, P. | |
| dc.date.accessioned | 2020-12-28T10:56:29Z | |
| dc.date.available | 2020-12-28T10:56:29Z | |
| dc.date.issued | 2020 | |
| dc.description.abstract | We report the Pd(II)-catalyzed picolinamide-aided ortho-C−H arylation-, alkylation-, and halogenation (sp2 γ−C−H functionalization) of phenylglycinol substrates. Phenylglycinols are remarkable building blocks and have found different applications in synthetic organic and medicinal chemistry. This work is a contribution towards the expansion of the library of phenylglycinol scaffolds and also substrate scope development by using the Pd(II)-catalyzed bidentate directing group picolinamide-aided C−H activation tactic. | en_US |
| dc.identifier.citation | Asian Journal of Organic Chemistry | en_US |
| dc.identifier.other | https://doi.org/10.1002/ajoc.202000560 | |
| dc.identifier.uri | https://onlinelibrary.wiley.com/doi/10.1002/ajoc.202000560 | |
| dc.identifier.uri | http://hdl.handle.net/123456789/3427 | |
| dc.language.iso | en | en_US |
| dc.publisher | Wiley‐VCH GmbH | en_US |
| dc.subject | C−H activation | en_US |
| dc.subject | C−H functionalization | en_US |
| dc.subject | Palladium | en_US |
| dc.subject | Phenylglycinol | en_US |
| dc.title | Pd(II)‐catalyzed, Picolinamide‐aided sp2 γ−C−H Functionalization of Phenylglycinol: Access to γ−C−H Arylated, Alkylated and Halogenated Phenylglycinol Scaffolds | en_US |
| dc.type | Article | en_US |