Exploitation of Intramolecular Glaser-Eglinton-Hay Macrocyclization for the Synthesis of New Classes of Optically Active Aza-Oxo-Thia Polyether Macrocycles from Amino Alcohol Building Blocks
| dc.contributor.author | Babu, S.A. | |
| dc.date.accessioned | 2020-12-04T11:26:20Z | |
| dc.date.available | 2020-12-04T11:26:20Z | |
| dc.date.issued | 2017 | |
| dc.description.abstract | We report an intramolecular Glaser-Eglinton-Hay coupling as an unprecedented route for assembling optically active aza-oxo polyether macrocycles containing a 1,3-diyne unit from enantiopure amino alcohol building blocks and suitable linkers. Furthermore, the conversion of the 1,3-diyne unit of the aza-oxo polyether macrocycles into a thiophene ring led to the assembly of new classes of optically active aza-oxa-thia (heterotopic) polyether macrocycle analogues of classical 18-C-6 and 18-C-5 systems | en_US |
| dc.identifier.citation | Synlett, 28(2) | en_US |
| dc.identifier.other | 10.1055/s-0036-1588329 | |
| dc.identifier.uri | https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0036-1588329 | |
| dc.identifier.uri | http://hdl.handle.net/123456789/2703 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Georg Thieme Verlag | en_US |
| dc.subject | alkynes | en_US |
| dc.subject | amino alcohols | en_US |
| dc.subject | cross-coupling | en_US |
| dc.subject | crown compounds | en_US |
| dc.title | Exploitation of Intramolecular Glaser-Eglinton-Hay Macrocyclization for the Synthesis of New Classes of Optically Active Aza-Oxo-Thia Polyether Macrocycles from Amino Alcohol Building Blocks | en_US |
| dc.type | Article | en_US |