Additive-Driven Rhodium-Catalyzed [4+1]/[4+2] Annulations of N-Arylphthalazine-1,4-dione with α-Diazo Carbonyl Compounds
| dc.contributor.author | Mandal, S.K. | |
| dc.date.accessioned | 2020-11-18T09:05:58Z | |
| dc.date.available | 2020-11-18T09:05:58Z | |
| dc.date.issued | 2018 | |
| dc.description | Only IISERM authors are available in the record. | |
| dc.description.abstract | A Rh(III)-catalyzed strategy involving the [4+1] annulation of 2-arylphthalazine-1,4-diones with α-diazo carbonyl compounds was developed, accessing a series of unprecedented hydroxy-dihydroindazolo-fused phthalazines in good to excellent yields. By varying the additive, phthalazino-fused cinnolines were synthesized under Rh-catalyzed conditions via [4+2] annulation between the same starting materials. Notably, such two strategies showed a good functional group tolerance and high atom efficiency. | en_US |
| dc.identifier.citation | Journal of Organic Chemistry, 83(19), pp. 11661-11673. | en_US |
| dc.identifier.other | 10.1021/acs.joc.8b01630. | |
| dc.identifier.uri | https://pubs.acs.org/doi/10.1021/acs.joc.8b01630 | |
| dc.identifier.uri | http://hdl.handle.net/123456789/1787 | |
| dc.language.iso | en | en_US |
| dc.publisher | American Chemical Society | en_US |
| dc.subject | Carbonyl compounds | en_US |
| dc.subject | Diazo carbonyl compounds | en_US |
| dc.subject | Phthalazines | en_US |
| dc.subject | Rhodium compounds | en_US |
| dc.subject | Catalysis | en_US |
| dc.subject | Atom efficiency | en_US |
| dc.title | Additive-Driven Rhodium-Catalyzed [4+1]/[4+2] Annulations of N-Arylphthalazine-1,4-dione with α-Diazo Carbonyl Compounds | en_US |
| dc.type | Article | en_US |