Palladium–Catalyzed Allylic Etherification Using Organoboron Salts under mild Conditions

Abstract

An efficient and base free palladium catalyzed allylic etherification method was developed for the synthesis of allyl aryl ethers, which are useful synthons of pharmaceutically interesting chroman derivatives, using organoboron salts as a coupling partner under mild conditions. Using this protocol a wide range of allyl aryl ethers were obtained in good to excellent yields using a variety of allyl acetates and organoboron salts.