Binding of pyrimidine tract with RRM motif using U2AF65
| dc.contributor.author | Kumar, Shivam. | |
| dc.date.accessioned | 2021-09-20T11:27:58Z | |
| dc.date.available | 2021-09-20T11:27:58Z | |
| dc.date.issued | 2021-07-28 | |
| dc.description.abstract | To study the molecular mechanisms of the recognition of the 3 -splice-site-assosciated polypyrimidine tract RNA by the large subunit of the human U2 snRNP auxiliary factor U2AF65 as a key early step in pre-mRNA splicing. The tandem RNA recognition motif domains of U2AF65 adopt two remarkably dis- tinct domain arrangements in the absence or presence of a strong (that is, high affinity) polypyrimidine tract. | en_US |
| dc.guide | Sharma, Monika | |
| dc.identifier.uri | http://hdl.handle.net/123456789/3897 | |
| dc.language.iso | en | en_US |
| dc.publisher | IISERM | en_US |
| dc.subject | Binding | en_US |
| dc.subject | Pyrimidine | en_US |
| dc.subject | U2AF65 | en_US |
| dc.title | Binding of pyrimidine tract with RRM motif using U2AF65 | en_US |
| dc.type | Thesis | en_US |