Bi(OTf)3 Catalyzed Solvent Free Approach to Unsymmetrical Diaryl(2‐indolyl)methanes through 1,6‐Conjugate Addition of 3‐Substituted Indoles to para‐Quinone Methides

Abstract

An efficient 1,6‐conjugate addition of 3‐substituted indoles to para‐quinone methides (p‐QMs) using catalytic amount of Bi(OTf)3 is described. This mild and atom‐economical protocol allowed us to access unsymmetrical diaryl(2‐indolyl)methanes in moderate to excellent yields under solvent‐free grinding conditions.