N-Heterocyclic Carbene Catalyzed Highly Chemoselective Intermolecular Crossed Acyloin Condensation of Aromatic Aldehydes with Trifluoroacetaldehyde Ethyl Hemiacetal
| dc.contributor.author | Ramanjaneyulu, B.T. | |
| dc.contributor.author | Mahesh, S. | |
| dc.contributor.author | Anand, R.V. | |
| dc.date.accessioned | 2020-12-11T06:13:17Z | |
| dc.date.available | 2020-12-11T06:13:17Z | |
| dc.date.issued | 2015 | |
| dc.description.abstract | A highly chemoselective intermolecular crossed acyloin condensation between aromatic aldehydes and trifluoroacetaldehyde ethyl hemiacetal has been developed under mild reaction conditions using N-heterocyclic carbene as a catalyst. A wide range of aromatic aldehydes bearing electron-withdrawing and -donating substituents underwent a smooth transformation to their corresponding trifluoromethyl containing acyloin derivatives in moderate to good yields. | en_US |
| dc.identifier.citation | Organic Letters, 17 (1) pp. 6-9 | en_US |
| dc.identifier.other | 10.1021/ol502581b | |
| dc.identifier.uri | https://pubs.acs.org/doi/10.1021/ol502581b | |
| dc.identifier.uri | http://hdl.handle.net/123456789/3023 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | American Chemical Society | en_US |
| dc.subject | Aldehydes | en_US |
| dc.subject | Condensation | en_US |
| dc.subject | Catalysts | en_US |
| dc.subject | Chemical reactions | en_US |
| dc.title | N-Heterocyclic Carbene Catalyzed Highly Chemoselective Intermolecular Crossed Acyloin Condensation of Aromatic Aldehydes with Trifluoroacetaldehyde Ethyl Hemiacetal | en_US |
| dc.type | Article | en_US |