Browsing by Author Guptasarma, P.

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Issue DateTitleGuideTypeAuthor(s)
2016The Achilles’ Heel of “Ultrastable” Hyperthermophile Proteins: Submillimolar Concentrations of SDS Stimulate Rapid Conformational Change, Aggregation, and Amyloid Formation in Proteins Carrying Overall Positive Charge-ArticleKhan, J.M.; Sharma, Prerna; Arora, Kanika; Kishor, Nitin; Kaila, P.; Guptasarma, P.
2016Arsenic and 17-β-estradiol bind to each other and neutralize each other’s signaling effects-ArticleKumar, Sukhdeep; Guptasarma, P.
2014Calcium Binding to Beta-2-Microglobulin at Physiological Ph Drives the Occurrence of Conformational Changes Which Cause the Protein to Precipitate into Amorphous Forms That Subsequently Transform into Amyloid Aggregates-ArticleKumar, Sukhdeep; Sharma, Prerna; Arora, Kanika; Guptasarma, P.
2018Characterization of a mildly alkalophilic and thermostable recombinant Thermus thermophilus laccase with applications in decolourization of dyes-ArticleKumari, Arpana; Kishor, Nitin; Guptasarma, P.
2008Conformational behavior of polypeptides derived through simultaneous global conservative site-directed mutagenesis of chymotrypsin inhibitor 2-ArticleGuptasarma, P.
2016Creation of active TIM barrel enzymes through genetic fusion of half‐barrel domain constructs derived from two distantly related glycosyl hydrolases-ArticleSharma, Prerna; Kaila, P.; Guptasarma, P.
2008Design of a soluble mini-protein through tandem duplication of the minimally engineered beta hairpin 'tongue' motif of alpha-hemolysin-ArticleAhmed, S.; Guptasarma, P.
2015Direct N-terminal sequencing of polypeptides using a thermostable bacterial aminopeptidase and MALDI-TOF mass spectrometry-ArticleKishor, Nitin; Guptasarma, P.
2017Endoglucanase activity at a second site in Pyrococcus furiosus triosephosphate isomerase—Promiscuity or compensation for a metabolic handicap?-ArticleSharma, Prerna; Guptasarma, P.
2015Erratum to: Insufficient (Sub-native) Helix Content in Soluble/Solid Aggregates of Recombinant and Engineered Forms of IL-2 Throws Light on How Aggregated IL-2 is Biologically Active-ArticleFatima, Uzma; Guptasarma, P.
2008Expression, purification, refolding and characterization of a putative lysophospholipase from Pyrococcus furiosus: Retention of structure and lipase/esterase activity in the presence of water-miscible organic solvents at high temperatures-ArticleGuptasarma, P.
2008Folding behavior of a backbone- reversed protein: Reversible polyproline type II to β-sheet thermal transitions in retro-GroES multimers with GroES-like features-ArticleGuptasarma, P.
2014Hyperthermophile protein behavior: Partially-structured conformations of Pyrococcus furiosus rubredoxin monomers generated through forced cold-denaturation and refolding-ArticlePrakash, Satya; Guptasarma, P.
2012Insufficient (sub-native) helix content in soluble/solid aggregates of recombinant and engineered forms of IL-2 throws light on how aggregated IL-2 is biologically active-ArticleFatima, Uzma; Guptasarma, P.
2013Introduction of a thermophile-sourced ion pair network in the fourth beta/alpha unit of a psychophile-derived triosephosphate isomerase from Methanococcoides burtonii significantly increases its kinetic thermal stability-ArticleDhaunta, N.; Arora, Kanika; Guptasarma, P.
2014The Key to the Extraordinary Thermal Stability of P. furiosus Holo-Rubredoxin: Iron Binding-Guided Packing of a Core Aromatic Cluster Responsible for High Kinetic Stability of the Native Structure-ArticlePrakash, Satya; Sundd, M.; Guptasarma, P.
2018Nobel Prize in Chemistry – 2018: Speeding Up Protein Evolution-ArticleGuptasarma, P.
2008Partial destabilization of native structure by a combination of heat and denaturant facilitates cold denaturation in a hyperthermophile protein-ArticleGuptasarma, P.
2015Probing protease sensitivity of recombinant human erythropoietin reveals α3-α4 inter-helical loop as a stability determinant-ArticleGuptasarma, P.
2018Probing the excited state dynamics of Venus: origin of dual-emission in fluorescent proteins-ArticleDhamija, S.; Thakur, Bhisham; Guptasarma, P.; De, A.K.