Please use this identifier to cite or link to this item:
http://hdl.handle.net/123456789/1754Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Kaur, M. | - |
| dc.contributor.author | Dubey, A. | - |
| dc.contributor.author | Khatri, M. | - |
| dc.contributor.author | Sehrawat, S. | - |
| dc.date.accessioned | 2020-11-18T06:08:17Z | - |
| dc.date.available | 2020-11-18T06:08:17Z | - |
| dc.date.issued | 2019 | - |
| dc.identifier.citation | Toxicon, 172, pp. 15-18. | en_US |
| dc.identifier.other | https://doi.org/10.1016/j.toxicon.2019.10.240 | - |
| dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S0041010119307238?via%3Dihub | - |
| dc.identifier.uri | http://hdl.handle.net/123456789/1754 | - |
| dc.description.abstract | Despite continued destruction of human lives by snakebites, appreciable improvements in immunotherapies have not been made. We selected and characterized venom-specific single domain antibodies (sdAbs) from a constructed phage display library of camelid variable region of heavy chain of the heavy chain antibodies (VHHs). Secretory phospholipase A2-specific sdAbs neutralized venom-induced toxicity in vitro and in vivo. Such monoclonal sdAbs could serve as an alternative to help manage snakebites to save lives. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Elsevier | en_US |
| dc.subject | Phage display | en_US |
| dc.subject | Monoclonal Ab | en_US |
| dc.subject | sdAb | en_US |
| dc.subject | RVV envenoming | en_US |
| dc.title | Secretory PLA2 specific single domain antibody neutralizes Russell viper venom induced cellular and organismal toxicity | en_US |
| dc.type | Article | en_US |
| Appears in Collections: | Research Articles | |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| Need to add pdf.odt | 8.63 kB | OpenDocument Text | View/Open |
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