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http://hdl.handle.net/123456789/1847
Title: | A One-Pot Approach to 2,3-Diarylbenzo[b]furans through N-Heterocyclic Carbene-Catalyzed 1,6-Conjugate Addition Followed by Acid Mediated Dehydrative Annulation |
Authors: | Singh, Gurdeep Goswami, P. Sharma, Sonam Anand, R.V. |
Keywords: | Dehydrative Annulation 2,3-Diarylbenzo[b]furans N-Heterocyclic Carbene-Catalyzed |
Issue Date: | 2018 |
Publisher: | American Chemical Society |
Citation: | Journal of Organic Chemistry, 83(17), pp. 10546–10554 |
Abstract: | A one-pot protocol for the synthesis of 2,3-diarylbenzo[b]furan derivatives through an N-heterocyclic carbene catalyzed 1,6-conjugate addition of aromatic aldehydes to 2-hydroxyphenyl-substituted para-quinone methides followed by acid-mediated dehydrative annulation has been developed. This protocol allowed us to access a wide range of 2,3-diarylbenzo[b]furan derivatives in moderate to good yields. |
URI: | https://pubs.acs.org/doi/10.1021/acs.joc.8b01358 http://hdl.handle.net/123456789/1847 |
Appears in Collections: | Research Articles |
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