Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/1847
Title: A One-Pot Approach to 2,3-Diarylbenzo[b]furans through N-Heterocyclic Carbene-Catalyzed 1,6-Conjugate Addition Followed by Acid Mediated Dehydrative Annulation
Authors: Singh, Gurdeep
Goswami, P.
Sharma, Sonam
Anand, R.V.
Keywords: Dehydrative Annulation
2,3-Diarylbenzo[b]furans
N-Heterocyclic
Carbene-Catalyzed
Issue Date: 2018
Publisher: American Chemical Society
Citation: Journal of Organic Chemistry, 83(17), pp. 10546–10554
Abstract: A one-pot protocol for the synthesis of 2,3-diarylbenzo[b]furan derivatives through an N-heterocyclic carbene catalyzed 1,6-conjugate addition of aromatic aldehydes to 2-hydroxyphenyl-substituted para-quinone methides followed by acid-mediated dehydrative annulation has been developed. This protocol allowed us to access a wide range of 2,3-diarylbenzo[b]furan derivatives in moderate to good yields.
URI: https://pubs.acs.org/doi/10.1021/acs.joc.8b01358
http://hdl.handle.net/123456789/1847
Appears in Collections:Research Articles

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