Tandem One-Pot Approach to Access 1,2,3-Triazole-fused Isoindolines through Cu-Catalyzed 1,6-Conjugate Addition of Me3SiN3 to p-Quinone Methides followed by Intramolecular Click Cycloaddition

Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/1915

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DC Field	Value	Language
dc.contributor.author	Jadhav, A.S.	-
dc.contributor.author	Pankhade, Y.A.	-
dc.contributor.author	Anand, R.V.	-
dc.date.accessioned	2020-11-19T10:21:02Z	-
dc.date.available	2020-11-19T10:21:02Z	-
dc.date.issued	2018	-
dc.identifier.citation	Journal of Organic Chemistry, 83(15), pp. 8596-8606	en_US
dc.identifier.other	https://doi.org/10.1021/acs.joc.8b00573	-
dc.identifier.uri	https://pubs.acs.org/doi/10.1021/acs.joc.8b00573	-
dc.identifier.uri	http://hdl.handle.net/123456789/1915	-
dc.description.abstract	A Cu-catalyzed one-pot approach has been developed for the synthesis of 1,2,3-triazole-fused tricyclic heterocycles. This tandem approach actually involves the 1,6-conjugate addition of Me3SiN3 to o-alkynylated p-quinone methides followed by an intramolecular [3+2]-cycloaddition reaction. This protocol allowed us to access a wide range of 1,2,3-trazole-fused isoindoline derivatives in moderate to good yields.	en_US
dc.language.iso	en	en_US
dc.publisher	American Chemical Society	en_US
dc.subject	Cycloaddition Reactions	en_US
dc.subject	Arylation	en_US
dc.subject	Benzyne	en_US
dc.subject	Cycloaddition	en_US
dc.subject	Catalysis	en_US
dc.title	Tandem One-Pot Approach to Access 1,2,3-Triazole-fused Isoindolines through Cu-Catalyzed 1,6-Conjugate Addition of Me3SiN3 to p-Quinone Methides followed by Intramolecular Click Cycloaddition	en_US
dc.type	Article	en_US
Appears in Collections:	Research Articles

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