Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/2189
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dc.contributor.authorDalal, A.-
dc.contributor.authorSingh, Prabhakar-
dc.contributor.authorBabu, S.A.-
dc.date.accessioned2020-11-25T07:03:31Z-
dc.date.available2020-11-25T07:03:31Z-
dc.date.issued2019-
dc.identifier.citationTetrahedron, 75(9), pp.1246-1257.en_US
dc.identifier.otherhttps://doi.org/10.1016/j.tet.2019.01.042-
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S004040201930081X-
dc.identifier.urihttp://hdl.handle.net/123456789/2189-
dc.description.abstractA one-pot, multicomponent-type, solvent-free Pd(II)-catalyzed direct β-C-H activation/arylation of carboxamides involving anhydrides as substrates via in situ installation of directing group (DG) is reported. Typically, the DG-assisted β-C-H activation/arylation of carboxamides is a two-step process comprising the installation of DG and Pd(II)-catalyzed Csingle bondH arylation. We attempted a multicomponent-type reaction comprising an anhydride, a DG (e.g. 8-aminoquinoline), an aryl iodide in the presence of the Pd(II) catalyst and an appropriate additive. Different anhydrides, DGs, aryl iodides, catalysts and additives were screened to reveal the scope of this multicomponent-type Csingle bondH arylation reaction process and various β-C-H arylated carboxamides were obtained in satisfactory to good yields.en_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.subjectMulticomponent-typeen_US
dc.subjectTypicallyen_US
dc.subjectCarboxamidesen_US
dc.titleOne-pot, solvent-free Pd(II)-catalyzed direct β-C-H arylation of carboxamides involving anhydrides as substrates via in situ installation of directing groupen_US
dc.typeArticleen_US
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