Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/2239
Full metadata record
DC FieldValueLanguage
dc.contributor.authorTiwari, Prince-
dc.contributor.authorMrigwani, Arpita-
dc.contributor.authorKaur, Harpreet-
dc.contributor.authorKaila, P.-
dc.contributor.authorKumar, Rajendra-
dc.contributor.authorGuptasarma, P.-
dc.date.accessioned2020-11-26T05:11:19Z-
dc.date.available2020-11-26T05:11:19Z-
dc.date.issued2018-
dc.identifier.citationAdvances in Experimental Medicine and Biology, 1112, pp. 107-138en_US
dc.identifier.otherDOI: 10.1007/978-981-13-3065-0_9-
dc.identifier.urihttps://link.springer.com/chapter/10.1007/978-981-13-3065-0_9-
dc.identifier.urihttp://hdl.handle.net/123456789/2239-
dc.description.abstractThis article begins with a general review of cell adhesion molecules (CAMs) and narrows the focus down progressively to the cadherins (calcium binding-dependent CAMs), classifications of subfamilies of the cadherins, type I (E- and N-) cadherins, evolutionary relationships amongst cadherins, structural-mechanical and functional consequences of calcium binding to the cadherins, differential molecular interactions involving the extracellular (ecto) and intracellular (cytoplasmic) domains of the cadherins, multiple adherence-related homophilic and heterophilic interactions and associated functions of E- and N-cadherin in organismal development and disease and cadherin trafficking and membrane rafts. It ends by summarizing multiple perspectives and hypotheses concerning different aspects of cadherin structure, stability and function.en_US
dc.language.isoenen_US
dc.publisherSpringer New York LLCen_US
dc.subjectCell adhesionen_US
dc.subjectNeuronal cadherinsen_US
dc.subjectCadherin interactionsen_US
dc.subjectCalcium bindingen_US
dc.subjectMetastasis Developmenten_US
dc.subjectCanceren_US
dc.titleStructural-Mechanical and Biochemical Functions of Classical Cadherins at Cellular Junctions: A Review and Some Hypothesesen_US
dc.typeArticleen_US
Appears in Collections:Research Articles

Files in This Item:
File Description SizeFormat 
Need to add pdf.odt8.63 kBOpenDocument TextView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.