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http://hdl.handle.net/123456789/2663| Title: | 1,6-Conjugate addition of zinc alkyls to para-quinone methides in a continuous-flow microreactor† |
| Authors: | Jadhav, A.S. Anand, R.V. |
| Keywords: | Dialkylzinc Efficient Synthesis |
| Issue Date: | 2017 |
| Publisher: | Royal Society of Chemistry |
| Citation: | Organic and Biomolecular Chemistry, 15(1), pp. 56-60. |
| Abstract: | An efficient method for the synthesis of alkyl diarylmethanes through the 1,6-conjugate addition of dialkylzinc reagents to para-quinone methides (p-QMs) has been developed under continuous flow conditions using a microreactor. This protocol allows to access unsymmetrical alkyl diarylmethanes in moderate to excellent yields using a wide range of p-QMs and dialkylzinc reagents. Interestingly, this transformation worked well without the requirement of a catalyst. |
| URI: | https://pubs.rsc.org/en/content/articlelanding/2017/ob/c6ob02277d#!divAbstract http://hdl.handle.net/123456789/2663 |
| Appears in Collections: | Research Articles |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| Need to add pdf.odt | 8.63 kB | OpenDocument Text | View/Open |
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