
Please use this identifier to cite or link to this item:
http://hdl.handle.net/123456789/2668
Title: | Catalytic aspects of a nickel(II)–bipyridine complex towards phosphatase and catechol dioxygenase activity |
Authors: | Yadav, H.R. Choudhury, A.R. |
Keywords: | Nickel(II) Crystal structure Phosphatase activity Catechol dioxygenase activity Bio-catalytic |
Issue Date: | 2017 |
Publisher: | Elsevier |
Citation: | Polyhedron, 129, pp. 114-122 |
Abstract: | A mononuclear nickel(II) complex, [Ni(bpy)2(OH2)(NO3)](NO3) (1) [bpy = 2,2′-bipyridine], has been synthesised and structurally characterised by routine analytical techniques including a single crystal X-ray diffraction study. X-ray crystal structure analysis shows that 1 crystallises in the triclinic system with the space group and adopts an octahedral geometry. The nickel(II) complex has been evaluated as a functional model for phosphatase and catechol dioxygenase enzymes by using 4-nitrophenylphosphate (PNPP) and 3,5-di-tert-butylcatechol (DTBC) as model substrates in aqueous-DMF and acetonitrile media respectively. This mononuclear nickel complex exhibits good hydrolytic phosphoester cleavage efficiency, viz. a kcat value of 8.42 × 103 h−1, and produces mostly benzoquinone (kobs = 2.3 × 10−3 min−1) and intradiol cleavage products during an investigation of catechol dioxygenase activity. |
Description: | Only IISERM authors are available in the record. |
URI: | https://www.sciencedirect.com/science/article/pii/S0277538717302346?via%3Dihub http://hdl.handle.net/123456789/2668 |
Appears in Collections: | Research Articles |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Need to add pdf.odt | 7.9 kB | OpenDocument Text | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.