Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/3897
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dc.contributor.authorKumar, Shivam.-
dc.date.accessioned2021-09-20T11:27:58Z-
dc.date.available2021-09-20T11:27:58Z-
dc.date.issued2021-07-28-
dc.identifier.urihttp://hdl.handle.net/123456789/3897-
dc.description.abstractTo study the molecular mechanisms of the recognition of the 3 -splice-site-assosciated polypyrimidine tract RNA by the large subunit of the human U2 snRNP auxiliary factor U2AF65 as a key early step in pre-mRNA splicing. The tandem RNA recognition motif domains of U2AF65 adopt two remarkably dis- tinct domain arrangements in the absence or presence of a strong (that is, high affinity) polypyrimidine tract.en_US
dc.language.isoenen_US
dc.publisherIISERMen_US
dc.subjectBindingen_US
dc.subjectPyrimidineen_US
dc.subjectU2AF65en_US
dc.titleBinding of pyrimidine tract with RRM motif using U2AF65en_US
dc.typeThesisen_US
dc.guideSharma, Monika-
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