Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/573
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dc.contributor.authorThapliyal, Saurabh-
dc.date.accessioned2016-08-08T08:34:17Z-
dc.date.available2016-08-08T08:34:17Z-
dc.date.issued2016-08-08-
dc.identifier.urihttp://hdl.handle.net/123456789/573-
dc.description.abstractCREB is a transcription factor. CREB is known to regulate expression of various genes involved in different functions. We found that CREB regulates expression of neuropeptide FLP-18 in C.elegans. FLP-18 is known to effect backward movement in C.elegans. Further we go on to show that CREB controls length of backward movement in C.elegans. Mutation in CREB homolog crh-1 resulted in decreased length of backward movement. This phenotype was rescued by expressing repressor isoform of CREB, CRH-1f in crh-1 mutants. These results suggests that CREB regulate FLP-18 expression and length of backward movement during exploratory behavior in C.elegansen_US
dc.description.sponsorshipIISER-Men_US
dc.language.isoenen_US
dc.publisherIISER-Men_US
dc.subjectBiologyen_US
dc.subjectCREBen_US
dc.subjectC.elegansen_US
dc.subjectGenesen_US
dc.subjectNeuropeptideen_US
dc.titleCREB Regulates Expression of Neuropeptide FLP-18 and Controls Backward Movementen_US
dc.typeThesisen_US
dc.guideBabu, Kavita-
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